Sox21 Modulates Sox2 Initiated Differentiation Of Epithelial Cells In Basal cells were mainly sox2 low sox21 low (80.5%), while ciliated cells were either sox2 high sox21 high (77.7%) or sox2 high sox21 low (14.5%; figure 4c). in the adult mouse te, sox2 and sox21 levels were similar between cell types in vivo ( figure 5a ), suggesting that these are stable for the maintenance of te and only increase when. Here, we describe patterning of the mouse proximal airway epithelium by sox21, which coincides with high levels of sox2 during development. airway progenitor cells in this sox2 sox21 zone show differentiation to basal cells, specifying cells for the extrapulmonary airways. loss of sox21 showed an increased differentiation of sox2 progenitor.
Figures And Data In Sox21 Modulates Sox2 Initiated Differentiation Of Thank you for submitting your article "sox21 modulates sox2 initiated differentiation of epithelial cells in the extrapulmonary airways" for consideration by elife. your article has been reviewed by 3 peer reviewers, one of whom is a member of our board of reviewing editors, and the evaluation has been overseen by edward morrisey as the senior. (a) immunostaining on sections of the main bronchi immediately distal of the carina from mice at embryonic day (e) 12.5, 13.5, 14.5, and 15.5 using sox2 (blue), sox21 (red), and either sox9 (green, top row) or smooth muscle acti. Sox2 expression levels are crucial for the balance between maintenance and differentiation of airway progenitor cells during development and regeneration. here, we describe sox21 patterning of the proximal airway epithelium which coincides with high levels of sox2. airway progenitor cells in this sox2 sox21 zone show differentiation to basal cells, specifying cells for the extrapulmonary. Using fetal lung organoids and adult bronchial epithelial cells, we show that sox2 sox21 regionalization is conserved in human. thus sox21 modulates sox2 initiated differentiation in.
Sox21 Modulates Sox2 Initiated Differentiation Of Epithelial Cells In Sox2 expression levels are crucial for the balance between maintenance and differentiation of airway progenitor cells during development and regeneration. here, we describe sox21 patterning of the proximal airway epithelium which coincides with high levels of sox2. airway progenitor cells in this sox2 sox21 zone show differentiation to basal cells, specifying cells for the extrapulmonary. Using fetal lung organoids and adult bronchial epithelial cells, we show that sox2 sox21 regionalization is conserved in human. thus sox21 modulates sox2 initiated differentiation in. [show full abstract] sox2 initiated differentiation of epithelial cells in the airways (eenjes, 2021). here, we show that precursor ne cells start to develop in the sox2 sox21 airway region and. Sox21 modulates sox2 initiated differentiation of epithelial cells in the extrapulmonary airways.
Figures And Data In Sox21 Modulates Sox2 Initiated Differentiation Of [show full abstract] sox2 initiated differentiation of epithelial cells in the airways (eenjes, 2021). here, we show that precursor ne cells start to develop in the sox2 sox21 airway region and. Sox21 modulates sox2 initiated differentiation of epithelial cells in the extrapulmonary airways.
Sox21 Modulates Sox2 Initiated Differentiation Of Epithelial Cells In
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